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Development of DNA analysis for human diseases. Sickle cell anemia and thalassemia as a paradigm

Y W Kan1

  • 1Howard Hughes Medical Institute Laboratory, Department of Laboratory Medicine, San Francisco, CA.

JAMA
|March 18, 1992
PubMed
Abstract

No abstract available in PubMed .

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Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...

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