Related Experiment Video
Updated: Aug 22, 2026

Disposable Dosators Intended for Dry Powder Delivery to Mice
Published on: August 18, 2023
Injection risk behaviors among clients of syringe exchange programs with different syringe dispensation policies
Alex H Kral1, Rachel Anderson, Neil M Flynn
1Urban Health Study, Department of Family and Community Medicine, University of California, San Francisco, CA 94110, USA. alkral@itsa.ucsf.edu
Abstract:
While there have been numerous papers published in the medical, social, and epidemiologic literature about the effectiveness of syringe exchange programs (SEPs), few papers identify operational characteristics of the SEPs they study or assess which of those characteristics are associated with optimal HIV risk reduction among clients. The objective of this study was to examine whether different syringe dispensation policies were associated with client-level injection-related HIV risk. Injection drug users (IDUs) were recruited at 23 SEPs in California in 2001 (n = 531). SEPs were classified by their executive directors as to whether they provided a strict one-for-one syringe exchange, gave a few extra syringes above the one-for-one exchange, or distributed the amount of syringes based upon need as opposed to how many syringes were turned in by the clients. Injection-related risk was compared by SEP program type. In multivariate logistic regression analysis, clients of distribution-based programs had lower odds of reusing syringes (adjusted odds ratio = 0.43; 95% CI = 0.27, 0.71) when adjusting for confounding variables. There were no statistical differences with regards to distributive or receptive syringe sharing by dispensation policy. It is concluded that SEPs that base syringe dispensation policy upon need may facilitate reductions in reuse of syringes.
Related Concept Videos
Drug Accumulation During Multiple Dosing: Repetitive IV Injections
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Pharmaceutical Poisoning: Potential Scenarios
