Related Experiment Video
Updated: Aug 22, 2026

Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
Published on: November 23, 2014
The relationship between location, color, and vessel structure within capillary vascular malformations
Vivek Sivarajan1, Iain R MacKay
1Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary, United Kingdom. viveksivarajan@hotmail.com
Abstract:
The treatment of capillary vascular malformations by laser is well established. Despite this, only a minority of patients obtain full clearance of their lesion after treatment. Both anatomic location and color have been proposed as prognostic factors determining the amount of improvement seen after laser treatment. This study uses the technique of depth measuring video microscopy to examine the hypothesis that smaller and more deeply placed capillaries may be responsible for the poorer response seen in certain anatomic locations. Fifty sites on 44 previously untreated patients were examined resting in a temperature-controlled room at 28 degrees C. No statistically significant correlation was found between color, based on a Munsell color chart recording and capillary depth or diameter. Also, no correlation was found between diameter, depth, or type of capillary ectasia and anatomic site. The authors believe that other factors, such as alteration in blood flow between different anatomic regions, and not vessel morphology alone, may be responsible for this variation in response.
Related Concept Videos
Overview of the Vascular System
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Regulation of Angiogenesis and Blood Supply
Mechanism of Angiogenesis
Structure of Blood Vessels

