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Cervical angina caused by atlantoaxial instability

Yoshiyuki Ito1, Nobuhiro Tanaka, Yoshinori Fujimoto

  • 1Department of Orthopaedic Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. yoito@hiroshima-u.ac.jp

Insights

Cervical angina, chest pain mimicking cardiac issues, can stem from atlantoaxial instability. Surgical fusion resolved symptoms, highlighting the importance of cervical spine evaluation for unexplained precordialgia.

Area of Science:

  • Neurology
  • Orthopedics
  • Cardiology

Background:

  • Cervical angina is precordialgia resembling cardiac angina, often caused by cervical spondylosis compressing nerve roots.
  • Compression of the C7 ventral root is the most common etiology for cervical angina.

Observation:

  • A case of cervical angina was attributed to atlantoaxial instability, distinct from typical C7 root compression.
  • The patient presented with significant atlantoaxial instability but minimal C7 root compression.
  • Chest pain was triggered by neck movement and resolved after surgical fusion of the atlantoaxial joint.

Findings:

  • Diagnosis of cervical angina was confirmed, caused by spinal cord compression at the C1-C2 level.
  • The resolution of symptoms post-fusion, without direct C7 decompression, supports atlantoaxial instability as the cause.
  • Potential mechanisms include sympathetic nervous system perturbation or impaired pain modulation pathways.

Implications:

  • Physicians should consider cervical angina in patients with unexplained precordialgia, especially when cardiac evaluations are normal.
  • Evaluation of the cervical spine, particularly for atlantoaxial instability, is crucial for diagnosing this rare condition.
  • Atlantoaxial instability represents a key differential diagnosis for precordialgia.

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