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Cervical angina caused by atlantoaxial instability
Yoshiyuki Ito1, Nobuhiro Tanaka, Yoshinori Fujimoto
1Department of Orthopaedic Surgery, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. yoito@hiroshima-u.ac.jp
Insights
Cervical angina, chest pain mimicking cardiac issues, can stem from atlantoaxial instability. Surgical fusion resolved symptoms, highlighting the importance of cervical spine evaluation for unexplained precordialgia.
Area of Science:
- Neurology
- Orthopedics
- Cardiology
Background:
- Cervical angina is precordialgia resembling cardiac angina, often caused by cervical spondylosis compressing nerve roots.
- Compression of the C7 ventral root is the most common etiology for cervical angina.
Observation:
- A case of cervical angina was attributed to atlantoaxial instability, distinct from typical C7 root compression.
- The patient presented with significant atlantoaxial instability but minimal C7 root compression.
- Chest pain was triggered by neck movement and resolved after surgical fusion of the atlantoaxial joint.
Findings:
- Diagnosis of cervical angina was confirmed, caused by spinal cord compression at the C1-C2 level.
- The resolution of symptoms post-fusion, without direct C7 decompression, supports atlantoaxial instability as the cause.
- Potential mechanisms include sympathetic nervous system perturbation or impaired pain modulation pathways.
Implications:
- Physicians should consider cervical angina in patients with unexplained precordialgia, especially when cardiac evaluations are normal.
- Evaluation of the cervical spine, particularly for atlantoaxial instability, is crucial for diagnosing this rare condition.
- Atlantoaxial instability represents a key differential diagnosis for precordialgia.
Abstract:
Cervical angina is defined as a paroxysmal precordialgia that resembles true cardiac angina caused by cervical spondylosis. Cervical angina most commonly results from compression of the C7 ventral root. We present here a case of cervical angina caused by atlantoaxial instability. This case had marked atlantoaxial instability but no flexibility of the middle to lower levels of the cervical spine. Although there was mild C7 root compression on the radiologic findings, the chest pain was induced by neck motion, and the precordialgia disappeared after posterior atlantoaxial fusion without C7 root decompression. Therefore, we diagnosed this case as cervical angina caused by spinal cord compression at the C1-C2 level. It was speculated that a perturbation of the sympathetic nervous system or a hypofunction of the pain suppression pathway in the posterior horn of the spinal cord caused the pectoralgia. Although cervical angina is a rare disease, physicians should be aware of it; if there are no abnormal findings on cardiac examinations for angina pectoris, they should examine the cervical spine. Cervical angina due to atlantoaxial instability is one of the differential diagnoses of precordialgia.
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