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Updated: Aug 22, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
[Central retinal vein occlusion in a factor V leiden and G21210A prothrombin variant carrier]
J Suárez Baraza1, J Calzado Hinojosa, J M Caracena Ordóñez
1Servicio de Oftalmología II, Hospital Universitario Virgen de la Arrixaca, Cátedra de Oftalmología, Universidad de Murcia, Spain.
Case Report:
A fifty-five year old man complained of diminished visual acuity in his right eye and reported a deep venous thrombosis in his right leg five years ago. Examination showed a central retinal vein occlusion in the right eye. Mutations in the factor V gene and prothrombin gene were found in a thrombophilia study. The patient was anticoagulated and no laser photocoagulation was required.
Discussion:
Various coagulation disorders induced by genetic mutations are often associated with an increased risk for retinal vein occlusion although there are no statistically significant associations reported in the literature.
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