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Updated: Aug 22, 2026

In vivo 19F MRI for Cell Tracking
Published on: November 25, 2013
Localized in vivo human 1H MRS at very short echo times
1Medical Department, Brookhaven National Laboratory, Upton, New York, USA. kzhong@cogsci.ibp.ac.cn
Abstract:
A new point-resolved spectroscopy (PRESS) sequence was developed that allows localized human proton MR spectra to be acquired at echo times (TEs) of 10 ms or less. The method was implemented on a 4 Tesla Varian research console and a clinical 3 Tesla Siemens Trio scanner. Human brain spectra acquired in vivo from the prefrontal cortex at TE=8 ms showed improved signals from coupled resonances (such as glutamate, glutamine, and myo-inositol) compared to spectra acquired at TE=30 ms. These improvements should result in more accurate quantitation of these metabolites.

