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Procedural efficacy and complications of X-Sizer thrombectomy in de novo and stented lesions

Gordon E Pate1, Robert Lowe, Arun Kuchela

  • 1Division of Cardiology, St. Paul's Hospital and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|September 25, 2004
PubMed

Insights

The X-Sizer thrombectomy device improved blood flow in patients with angiographic thrombus. However, careful use is advised, especially for in-stent thrombosis, as it may not prevent distal embolization.

Area of Science:

  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Angiographic thrombus presence correlates with adverse procedural and clinical outcomes.
  • Thrombectomy devices aim to improve outcomes by removing thrombus.
  • The X-Sizer thrombectomy device is evaluated for its efficacy and safety.

Purpose of the Study:

  • To report the clinical experience with the X-Sizer thrombectomy device.
  • To assess the device's effectiveness in improving blood flow (TIMI flow).
  • To identify complications associated with X-Sizer thrombectomy.

Main Methods:

  • Retrospective review of 44 patients treated with the X-Sizer device from March 2001 to December 2002.
  • Indications included myocardial infarction, unstable angina, and stent thrombosis.
  • Procedural success, TIMI flow changes, and complications were recorded.

Main Results:

  • Successful deployment in 42 out of 44 patients.
  • Median TIMI flow improved from 1 to 2 post-thrombectomy (P=0.01), with a median final TIMI flow of 3.
  • Complications included distal macro-embolization (4) and transient no-reflow (5). Difficulty was noted in treating in-stent thrombosis.

Conclusions:

  • The X-Sizer thrombectomy device can effectively improve TIMI flow.
  • The device is associated with potential complications, including distal embolization.
  • Caution is warranted when using the X-Sizer device for in-stent thrombosis.

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