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Left ventricular involvement in right ventricular dysplasia.
B Pinamonti1, G Sinagra, A Salvi
1Department of Cardiology, Ospedale Maggiore, Trieste, Italy.
American Heart Journal
|March 1, 1992
Summary
Right ventricular dysplasia, a heart muscle disease, can affect the left ventricle. This study found that left ventricular involvement is present in some patients and may worsen over time.
Area of Science:
- Cardiology
- Pathology
Background:
- Right ventricular dysplasia (RVD) is a heart muscle disease typically affecting only the right ventricle.
- RVD involves the replacement of myocardial muscle with adipose or fibroadipose tissue.
- Left ventricular (LV) involvement in RVD is infrequently reported.
Purpose of the Study:
- To determine the prevalence and characteristics of LV involvement in RVD.
- To assess the potential progression of LV abnormalities in RVD patients.
Main Methods:
- Thirty-nine patients with RVD underwent M-mode and 2D echocardiography.
- Cardiac catheterization was performed in 28 patients.
- Endomyocardial biopsy was conducted in 25 patients.
Main Results:
- Left ventricular involvement was observed in 14 of 39 patients at initial examination.
- LV involvement manifested as asynergic areas or diffuse hypokinesis.
- During follow-up, 9 out of 27 patients showed new or worsening LV abnormalities; 10 had worsening RV function.
Conclusions:
- Right ventricular dysplasia can be associated with left ventricular involvement.
- The disease progression in RVD may include the development or worsening of left ventricular abnormalities.
- RVD is not exclusively a right ventricular disorder and can impact overall cardiac function.