Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Hypertensive-ischemic leg ulcers.

E M FARBER, O E L SCHMIDT

California Medicine

|January 1, 1950

Summary

This summary is machine-generated.

Hypertension can cause unique leg ulcers above the ankle. These ischemic ulcers present with purplish discoloration and tenderness, linked to arteriolar changes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Clinical testing of new drugs for lesional skin diseases such as psoriasis A new delivery system.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2016

Same author

Evaluation of beta-dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in the treatment of urticaria, scleroderma and allied disturbances.

Proceedings of the staff meetings. Mayo Clinic·2010

Same author

Ulcer of the leg due to arteriolosclerosis and ischemia, occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers).

Proceedings of the staff meetings. Mayo Clinic·2010

Same author

Benadryl in the treatment of urticaria.

Proceedings of the staff meetings. Mayo Clinic·2010

Same author

Hydroa estivale.

Archives of dermatology and syphilology·2010

Same author

Ulcer of the leg due to arteriosclerosis and ischemia occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers) a preliminary report.

Proceedings [of the] annual meeting. Central Society for Clinical Research (U.S.)·2010

Same journal

Observations on mass x-ray surveys.

California medicine·2010

Same journal

Health education and the democratic process.

California medicine·2010

Same journal

Evolution of chemotherapy in tuberculosis.

California medicine·2010

Same journal

Trends of tuberculosis association programs.

California medicine·2010

Same journal

The treatment of subacute bacterial endocarditis.

California medicine·2010

Same journal

[CASE history: polyarteritis nodosa with massive involvement of the kidney masqueraded as acute glomerular nephritis].

California medicine·2010

See all related articles

Area of Science:

Vascular Medicine
Dermatology
Pathology

Background:

Hypertensive patients, particularly women, have been observed with leg ulcers distinct from common types.
These unique ulcers typically manifest above the ankle.
Initial presentation involves purplish discoloration at minor trauma sites, progressing to painful ulceration.

Purpose of the Study:

To characterize the distinct features of leg ulcers observed in hypertensive patients.
To investigate the underlying pathological changes in these specific ulcer types.

Main Methods:

Histopathological examination of tissue samples from ulcer margins and bases.
Clinical observation of ulcer presentation and progression in affected patients.

Keywords:

Related Experiment Videos

Main Results:

Obliterative arteriolar sclerotic changes were identified in ulcer tissue.
Ischemic-appearing connective tissue and inflammatory changes were noted.
The ulcers exhibit characteristics different from ordinary leg ulcers.

Conclusions:

The observed leg ulcers in hypertensive patients are associated with specific arteriolar sclerotic and ischemic changes.
These findings highlight a distinct clinical and pathological entity in vascular medicine.
Further investigation into these unique ulcers is warranted.