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Related Experiment Videos

Tuberculous keratoconjunctivitis.

W A Aclimandos1, M Kerr-Muir

  • 1King's College, London.

The British Journal of Ophthalmology
|March 1, 1992
PubMed
Summary
This summary is machine-generated.

A young boy

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Pulmonology

Background:

  • A 15-year-old West Indian boy presented with unilateral keratoconjunctivitis (KC), initially misdiagnosed as allergic.
  • The patient subsequently developed a facial vesicular rash, leading to suspicion of herpes simplex virus infection.

Observation:

  • Despite negative viral cultures and poor response to antiviral therapy, the KC progressed to bilateral involvement, significantly reducing visual acuity.
  • Systemic symptoms included fatigue, pyrexia, generalized lymphadenopathy, and a lung mass suggestive of granulomatous disease.

Findings:

  • A non-caseating granuloma obstructing the bronchus was identified, but acid-fast bacilli were absent in sputum and bronchial washings.
  • A strongly positive Heaf test indicated tuberculosis (TB).

Implications:

  • Prompt initiation of anti-tuberculous treatment resulted in rapid resolution of both systemic and ocular manifestations.
  • This case highlights the importance of considering TB in the differential diagnosis of atypical KC and respiratory symptoms, especially in endemic areas.