Related Experiment Video

Updated: Oct 13, 2026

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen
07:54

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

Published on: September 20, 2012

[On the determination of changes in the large periodic structure of collagen (author's transl)]

T Nemetschek, R Jonak, H Nemetschek-Gansler

    Zeitschrift Fur Naturforschung. Section C, Biosciences
    |November 1, 1978
    PubMed

    More Related Videos

    Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo10:24

    Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo

    Published on: May 9, 2016

    Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools07:58

    Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

    Published on: November 11, 2020

    Related Concept Videos

    Structural Protein Function01:56

    Structural Protein Function

    Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
    Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to form...
    Assembly of Cytoskeletal Filaments01:18

    Assembly of Cytoskeletal Filaments

    Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
    Collagens are the Major Structural Proteins of ECM01:13

    Collagens are the Major Structural Proteins of ECM

    Three main types of fibers are secreted by fibroblasts: collagen fibers, elastic fibers, and reticular fibers. Collagen fiber is made from fibrous protein subunits linked together to form a long, straight fiber. Collagen fibers, while flexible, have great tensile strength, resist stretching, and give ligaments and tendons their characteristic resilience and strength. These fibers hold connective tissues together, even during the body's movement.
    Connective tissue proper includes loose...
    Fibril-associated Collagen01:11

    Fibril-associated Collagen

    Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
    For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
    Type IV Collagen of Basal Lamina01:05

    Type IV Collagen of Basal Lamina

    Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen  forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
    A type IV collagen molecule has six alpha chains which can exist in...
    Dense Connective Tissue01:13

    Dense Connective Tissue

    Dense connective tissue contains more collagen fibers than loose connective tissue. As a consequence, it displays greater resistance to stretching. There are two major categories of dense connective tissue— regular and irregular.
    Dense Regular Connective Tissue
    In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...