Related Experiment Video

Updated: Aug 22, 2026

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials
10:50

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials

Published on: April 10, 2016

The activation effect of calcium on a bactericidal substance for Bacillus subtilis in human serum

R F JACOX

    The Journal of Experimental Medicine
    |August 1, 1950
    PubMed

    An enhanced bactericidal activity of human serum for B. subtilis develops during many different forms of illness, e.g. carcinoma, virus and bacterial infections, and during acute coronary occlusion. This increased bactericidal effect cannot be related to leucocytosis, fever, serum complement, C-reactive protein, or a specific antibody reaction. The serum bactericidal factor becomes inactive in decalcified serum, but active again when optimal concentrations of calcium are added. Magnesium does not cause reactivation.

    Keywords:
    BACTERIABLOOD

    More Related Videos

    Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry07:28

    Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry

    Published on: October 29, 2020

    Related Concept Videos

    Calmodulin-dependent Signaling01:16

    Calmodulin-dependent Signaling

    Calmodulin (CaM) is a calcium-binding protein in eukaryotes that controls various calcium-regulated cellular processes. It has four calcium-binding sites that bind calcium to form the calcium-calmodulin ( Ca2+-CaM) complex. GPCR stimulation increases the calcium levels in the cells that bind to CaM and induces a conformational change.
    The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...