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Autoimmune hemolytic anemia associated with anti-Sc1
I Owen1, V Chowdhury, M E Reid
1Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
Transfusion
|February 1, 1992
Abstract:
A case of autoimmune hemolytic anemia (AIHA) in a young child is described. The hemolysis was resistant to steroid therapy but responded to splenectomy and intravenous immunoglobulin. The autoantibody was shown to be anti-Sc1 by both serologic and immunoblotting techniques. This seems to be the first report of an autoanti-Sc1 detected by immunoblotting and the first example of AIHA in a child caused by autoanti-Sc1.