Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Alcohol and cancer.

¹Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, Maryland 20892.

Cancer Research

|April 1, 1992

Summary

This summary is machine-generated.

Alcohol consumption increases human cancer risks, particularly for oral, throat, and liver cancers. While ethanol is implicated, the exact mechanisms driving these alcohol-related cancer risks require further investigation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Timing of HPV16-E6 antibody seroconversion before OPSCC: findings from the HPVC3 consortium.

Annals of oncology : official journal of the European Society for Medical Oncology·2019

Same author

Vitamin B6 catabolism and lung cancer risk: results from the Lung Cancer Cohort Consortium (LC3).

Annals of oncology : official journal of the European Society for Medical Oncology·2019

Same author

No association between circulating concentrations of vitamin D and risk of lung cancer: an analysis in 20 prospective studies in the Lung Cancer Cohort Consortium (LC3).

Annals of oncology : official journal of the European Society for Medical Oncology·2018

Same author

Late adulthood mortality among African-American and white American people with Type 1 diabetes according to age at diabetes diagnosis.

Diabetic medicine : a journal of the British Diabetic Association·2018

Same author

The impact of sociodemographic factors and PSA screening among low-income Black and White men: data from the Southern Community Cohort Study.

Prostate cancer and prostatic diseases·2017

Same author

Association of oral microbiome with type 2 diabetes risk.

Journal of periodontal research·2017

Area of Science:

Oncology
Epidemiology
Toxicology

Background:

Ethanol consumption is a global health concern.
While not typically carcinogenic in animal models, alcoholic beverages are linked to human cancers.
The specific mechanisms of alcohol-induced carcinogenesis in humans remain unclear.

Purpose of the Study:

To review epidemiological evidence on alcohol consumption and cancer risk.
To explore characteristics of the alcohol-cancer association that may suggest causal pathways.
To synthesize current understanding of alcohol's role in human carcinogenesis.

Main Methods:

Systematic review of epidemiological studies.
Analysis of cancer risk associated with varying levels of alcohol consumption.

Related Experiment Videos

Examination of different types of alcoholic beverages and their cancer links.

Main Results:

Elevated risks for oral, pharyngeal, laryngeal, esophageal, and liver cancers are consistently observed with alcohol consumption.
Cancer risk typically correlates with the quantity of alcohol consumed.
Evidence suggests a link between alcohol and colorectal and breast cancers, though further confirmation is needed.

Conclusions:

Ethanol or its metabolites are likely etiological agents in alcohol-related cancers.
All beverage types appear to contribute to increased cancer risk.
Further research is needed to elucidate the precise mechanisms of alcohol-induced cancer in humans.