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Biochemical ethanol effects affected by a non-steroidal anti-inflammatory drug
M Zentella de Piña1, A Hernández-Tobías, Y Saldaña-Balmori
1Depto. de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, D.F.
FEBS Letters
|February 24, 1992
Abstract:
The non-steroidal anti-inflammatory drug, piroxicam, prevents the hepatic increase of triacylglycerols and malondialdehyde resulting from the acute intoxication of rats with ethanol. In addition, in the intoxicated rats, piroxicam consistently produces a decrease in the levels of blood ethanol in comparison with control animals. It is suggested that the anti-inflammatory compound stimulates ethanol oxidation.