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Updated: Aug 9, 2026
Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Retrieval of a well-functioning extensor mechanism allograft from a total knee arthroplasty. Clinical and
R S J Burnett1, V L Fornasier, C M Haydon
1London Health Sciences Center, 339 Windemere Road, 9th Floor 90F-2, University of Western Ontario, London, Ontario N6A 5A5, Canada.
Abstract:
We present the histological findings of an extensor mechanism allograft which was used in a total knee arthroplasty two years after implantation. Analysis of the graft was undertaken at four distinct anatomical levels and it was found to be incorporated into host tissue at each level. A wedge of fibrinoid necrosis, probably related to impingement of the graft on the tibial polyethylene insert, was seen. Impingement may play a role in the injury and necrosis of an allograft and may be one mode of failure in an extensor mechanism allograft.
