Related Experiment Video
Updated: Aug 21, 2026

Determination of Cardiac Output in a Porcine Model for Ex Vivo Pulmonary Perfusion
Published on: June 28, 2024
[A comparison of two methods for continuous cardiac output measurement: PulseCO VS CCO]
Masato Tsutsui1, Tomohisa Mori, Yoshihiko Aramaki
1Department of Anesthesiology, National Defense Medical College, Tokorozawa 359-8513.
Background:
PulseCO (PulseCO) (PulseCO Hemodynamic Monitor, LiDCO Co., London, England) is a low invasive apparatus to measure cardiac output continuously from arterial pulse waveform. CCO (774 HF 75, Edwards Lifescience Co., California, USA) is a continuous cardiac monitor commonly used clinically. The purpose of this study is to compare the accuracy of these two methods for cardiac output measurement with the thermodilution technique (TDCO) as control.
Methods:
To compare the accuracy of PulseCO with that of CCO, six patients with pulmonary-artery catheter inserted were recruited. PulseCO and CCO were measured continuously, and these CO values were compared with TDCO measurements every hour.
Results:
Correlation with TDCO was examined in PulseCO (r=0.82) and CCO (r=0.80).
Conclusions:
PulseCO was low invasive, and showed a significantly better correlation with TDCO, compared with CCO.
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