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Primary meningococcal conjunctivitis in an adult

Christopher M Andreoli1, Henry E Wiley, Marlene L Durand

  • 1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA. christopher_andreoli@hms.harvard.edu

Cornea
|September 28, 2004
PubMed
Abstract

Insights

Primary meningococcal conjunctivitis can mimic viral infections like epidemic keratoconjunctivitis. Prompt diagnosis and systemic antibiotics are crucial to prevent serious complications.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Primary meningococcal conjunctivitis is rare but can present with symptoms similar to epidemic keratoconjunctivitis.
  • Distinguishing between bacterial and viral causes of conjunctivitis is essential for appropriate treatment.

Observation:

  • A 28-year-old male presented with bilateral follicular conjunctivitis and subepithelial corneal infiltrates, initially suspected as adenoviral.
  • Initial diagnostic tests, including Gram stain, were negative, delaying the identification of Neisseria meningitidis.

Findings:

  • Conjunctival cultures confirmed Neisseria meningitidis infection.
  • The patient received systemic antibiotics and topical therapy, leading to resolution of conjunctivitis without systemic spread.

Implications:

  • This case highlights the importance of considering Neisseria meningitidis in the differential diagnosis of severe conjunctivitis, even with initial negative results.
  • Early and accurate diagnosis with appropriate systemic antibiotic treatment is critical to prevent potential bacteremic complications associated with meningococcal infections.

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