Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hyperosmolar nonketotic diabetic coma in children].

U Stolz, F Saur, E Gugler

    Helvetica Paediatrica Acta
    |July 1, 1977
    PubMed
    Summary

    Nonketotic hyperosmolar diabetic coma is a rare but serious complication of juvenile diabetes, particularly in children with Down's syndrome. This condition requires prompt medical attention due to its high mortality rate.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Inter-observer agreement of ultrasonographic measurement of alpha and beta angles and the final type classification based on the Graf method.

    Swiss medical weekly·2004
    Same author

    Significant and persistent improvement of thrombocytopenia after splenectomy in an adult with the Wiskott-Aldrich Syndrome and intra-cerebral bleeding.

    American journal of hematology·1995
    Same author

    Can paediatrics be kept vivacious in future?

    European journal of pediatrics·1995
    Same author

    Immunthrombocytopenic purpura as a model for pathogenesis and treatment of autoimmunity.

    European journal of pediatrics·1995
    Same author

    [Emergencies in children. Interview by Klaus Reinhardt].

    Therapeutische Umschau. Revue therapeutique·1994
    Same author

    [Acute dehydration in children].

    Therapeutische Umschau. Revue therapeutique·1994

    Area of Science:

    • Pediatrics
    • Endocrinology
    • Genetics

    Background:

    • Nonketotic hyperosmolar diabetic coma (NHDC) is an uncommon complication of juvenile diabetes mellitus.
    • NHDC is observed with higher frequency in children with Down's syndrome and psychomotor retardation.

    Observation:

    • A case of a 14-month-old girl with Down's syndrome presenting with NHDC is detailed.
    • The patient exhibited severe dehydration, extreme hyperglycemia, hyperosmolarity, and glucosuria without ketonuria.

    Findings:

    • NHDC in juvenile diabetes, especially in conjunction with Down's syndrome, presents a distinct clinical profile.
    • The mortality rate for NHDC in pediatric cases is notably high at 24%.

    Implications:

    • Early recognition and management of NHDC are crucial in pediatric patients, particularly those with genetic syndromes.
    • Further research into the pathogenetic mechanisms of NHDC in this population is warranted to improve outcomes.

    Related Experiment Videos