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Ocular pseudoexfoliation associated with hearing loss.

Reham I Shaban¹, Wafa M Asfour

¹Department of Ophthalmology, Royal Jordanian Medical Services, King Hussein Medical Center, Amman, Jordan.

Saudi Medical Journal

|September 28, 2004

Summary

Ocular pseudoexfoliation (PXF) is linked to sensorineural hearing loss. This study found most PXF patients had poorer hearing than controls, suggesting PXF is a systemic condition.

Area of Science:

Ophthalmology
Audiology
Systemic Diseases

Background:

Ocular pseudoexfoliation (PXF) is increasingly recognized as a systemic condition.
Evidence suggests PXF may affect organs beyond the eye.

Purpose of the Study:

To investigate the association between ocular pseudoexfoliation (PXF) and sensorineural hearing loss.
To compare hearing thresholds in PXF patients with age-matched controls.

Main Methods:

Prospective study of 41 patients with ocular PXF.
Pure tone hearing threshold measurements at 1, 2, and 3 kHz.
Comparison with International Standard (ISO 7029) median age-associated hearing loss (AAHL).

Main Results:

87% of PXF patients exhibited elevated hearing threshold levels (HTL) compared to AAHL.

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No significant correlation was found between glaucoma and sensorineural hearing loss.

The majority of patients demonstrated sensorineural hearing loss.

Conclusions:

A high prevalence of sensorineural hearing loss exists in patients with ocular PXF.
These findings support the concept of PXF as a systemic disease.
Further research into PXF's systemic manifestations is warranted.