Related Experiment Video
Updated: Aug 21, 2026

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
Published on: July 9, 2020
Critical pathways can improve results with carotid endarterectomy
Keith D Calligaro1, Kevin J Doerr, Sandy McAfee-Bennett
1Section of Vascular Surgery, Pennsylvania Hospital, Philadelphia 19106, USA.
Abstract:
Approximately 10 years ago, the Section of Vascular Surgery at Pennsylvania Hospital reported results of critical pathways that we developed for all major vascular operations, including carotid endarterectomy (CEA). After implementing these pathways, we then developed a specific five-step protocol to further improve results and decrease costs for elective CEA. With the advent of carotid artery balloon angioplasty and stenting (CABAS), CEA has come under increasing attack by endovascular interventionalists. We believe our regimen remains the gold-standard against which CABAS should be compared. Our five-step CEA protocol includes: (1) duplex ultrasonography performed in an accredited vascular laboratory as the sole diagnostic carotid preoperative study, (2) admission the day of surgery, (3) cervical block anesthesia to eliminate intraoperative electroencephalographic monitoring and other costly intraoperative monitoring tests, (4) transfer from the recovery room after a short observation period to the vascular ward, and (5) discharge the first postoperative morning. Since this 5-step protocol was implemented several years ago, we have found it to be safe and cost-effective, and now represents the standard against which CABAS should be compared.
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Coronary Artery Disease V: Interprofessional Care
Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
Cardiac Catheterization I: Pre-Procedure Overview
Peripheral Artery Disease V: Postoperative Nursing Management
Atherosclerosis III: Management