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Expression of the expanded YFL007w ORF and assignment of the gene name BLM10

Kevin Doherty1, Ajay Pramanik, Leah Pride

  • 1City University of New York Medical School, Department of Microbiology and Immunology, Science Building and Harris Hall, Convent Avenue at 138th Street, New York, NY 10031, USA.

Yeast (Chichester, England)
|September 28, 2004
PubMed

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Exon Recombination02:32

Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...