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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Lung abscesses and jaundice due to prolonged Escherichia coli bacteremia associated with pyelonephritis: a forgotten
H.J.T. Smalbraak1, A.E. Meinders, L.F.I.J. Oudenhoven
1Department of General Internal Medicine, Leiden University Medical Center, Building 1, C1-R45, PO-Box 9600, Leiden, 2300 RC, The Netherlands; Department of Radiology, Leiden University Medical Center, Building 1, C2-S1, P.O. Box 9600, Leiden 2300 RC, The Netherlands.
Abstract:
We describe a previously healthy, middle-aged patient with prolonged bacteremia and Escherichia coli presenting with jaundice and lung abscesses. At presentation, a paucity of respiratory signs and symptoms was found, although the patient appeared to be very ill. The cavitary pulmonary lesions and jaundice were due to hematogenous spread of E. coli from a pyelonephritis. Pulmonary abscesses and jaundice in the setting of prolonged bacteremia due to pyelonephritis was frequently observed before the antibiotic era. Nowadays, it is almost a forgotten phenomenon.
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