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Effect of dimephosphone (monophosphonate) on the course of pregnancy and fetal development in rats

R Kh Khafiz'yanova1, I M Burykin, G N Aleeva

  • 1Department of Pharmacology, Department of Normal Anatomy, Kazan State Medical University. rofija_kh@ mail.ru

Bulletin of Experimental Biology and Medicine
|September 29, 2004
PubMed

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...