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Updated: Jun 25, 2026

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
Published on: February 16, 2015
Immunotherapy for malignant gliomas: emphasis on strategies of active specific immunotherapy using autologous
Steven De Vleeschouwer1, Stefaan W Van Gool, Frank Van Calenbergh
1Department of Neurosurgery, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.
Review:
In this review, we discuss immunotherapy for malignant gliomas.
Emphasis:
The emphasis is on the novel strategy of active specific immunotherapy using dendritic cells as antigen-presenting cells, especially its theoretical concepts and advantages, specific requirements, critical issues, pre-clinical and early clinical experience. Dendritic cell vaccination is situated in the diversity of other immunotherapeutical approaches.
Further Discussion:
Future directions, challenges, and drawbacks will be discussed.
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