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Published on: September 10, 2018
First case of post-conception Verteporfin exposure: pregnancy and neonatal outcome
Marco De Santis1, Brigida Carducci, Lidia De Santis
1Telefono Rosso, Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Rome, Italy. marcodesantis@rm.unicatt.it
Purpose:
To assess pregnancy and neonatal outcomes in a woman accidentally exposed to Verteporfin photodynamic therapy in the third week of pregnancy.
Methods:
Post-conception counselling and prospective follow-up by telephone interview at Telefono Rosso (Teratology Information Service) were carried out. The baby was examined at birth and at 26 months.
Results:
The outcome of the pregnancy was normal and a healthy female child with a normal birthweight was born. The baby's follow-up was normal at 26 months.
Conclusions:
This is the first reported case of a childbearing woman being accidentally exposed to Verteporfin during pregnancy. No fetal or neonatal adverse effects were documented.
