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Isolation and Activation of Murine Lymphocytes
08:08

Isolation and Activation of Murine Lymphocytes

Published on: October 30, 2016

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation

Naoyuki Fujita1, David L Jaye, Cissy Geigerman

  • 1Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

Cell
|September 30, 2004
PubMed
Summary

MTA3 is a novel cofactor for the BCL-6 transcriptional repressor, crucial for B lymphocyte cell fate. MTA3 depletion impairs BCL-6 function, altering B cell development and plasma cell differentiation.

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