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Updated: Aug 21, 2026
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Electron microscopic characteristics of peripheral blood lymphocytes in children with infectious mononucleosis
O I Urazova1, V V Novitskii, A P Pomogaeva
1Department of Pathophysiology, Department of Childhood Infections, Siberian State Medical University, Tomsk, Russia. urazov@mail2000.ru
Abstract:
Infectious mononucleosis is associated with pronounced changes in surface architectonics of peripheral blood lymphocytes persisting during convalescence and remote period after the disease. The degree of these changes depends on the disease agent and age-specific characteristics of the body. The most pronounced and sustained disorders in the morphostructural organization of lymphocytes are caused by Epstein-Barr virus (in comparison with agents of other etiology); these disorders are more pronounced in children aged 7-14 years than in those aged 3-6 years.
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