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Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens
Published on: June 12, 2013
Invasive characteristics of apathogenic Shigella flexneri 5a2c mutant obtained under the effect of furazolidone
T N Efremova1, I G Gruzdeva, I V Matveev
1Department of Cell Cultures, Institute of Cytology, Russian Academy of Sciences, St. Petersburg.
Bulletin of Experimental Biology and Medicine
|September 30, 2004
Abstract:
Apathogenic Shigella flexneri 5a2c mutant treated with furazolidone can infect eucaryotic cells. These bacteria contain no virulence genes responsible for Sh. flexneri invasion, which seems to be the cause of their apathogenicity. The capacity of bacteria to penetrate into eucaryotic cells correlates with the appearance of ECP 32 protease specifically cleaving actin.
