Nitroxide synthase activity as a marker of early stages of experimental cartilage dysmetabolism
Related Experiment Video
Updated: Aug 21, 2026
08:32
A Pre-Clinical Model of Synovitis Using Ex vivo Human Synovial Tissue with Preserved Function and Architecture
Published on: March 20, 2026
A V Cherepovskii1, A I Dubikov, S V Nikulin
1Vladivostok State Medical Institute.
Bulletin of Experimental Biology and Medicine
|September 30, 2004
Abstract:
Time course of nitroxide synthase activity in the knee joint cartilage was studied in animals with experimental anterior instability of the knee joint. A significant increase in nitroxide synthase activity in chondrocytes was paralleled by a progressive decrease in glycosaminoglycan content in the cartilaginous matrix and subsequent destruction of the cartilage cytoarchitectonics.
