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Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
Published on: July 15, 2019
Coxsackie virus B 4 encephalitis in a 7 year old boy
J Brunner1, A Litwicki, S Aliani
1Department of Pediatrics, University of Saarland, Homburg/Saar, Germany. juergen.brunner@uklibk.ac.at
Background:
Enteroviruse belongs to the family of picornaviruses. They can be devided in 4 groups: polioviruses (Typ 1-3) enteric cythopathogenic human orphan (ECHO)- viruses, unclassified enteroviruses 68-71 and coxsackie viruses. Coxsackie virus type B can cause pharyngitis, myalgia, myocarditis and meningitis as well as severe neonatal infections.
Case Report:
We report a patient with coxsackie type B 4 encephalitis. A 7 year old boy had 2 episodes of mental dizziness and consciousness disturbance. Because of he presented a visus of 70 %, headaches and vomiting he was admitted to our hospital. In the cerebrospinal fluid a coxsackie virus type B 4 could be identified. With nonspecific therapy the boy recovered.
Conclusion:
We concluded that coxsackie virus B 4 caused acute encephalitis with ophthalmological and mental symptoms and good prognosis. Coxsackie virus B 4 should be considered in patients with encephalitis.
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