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A tuberculin skin test survey among Afghan children in Kabul

M Dubuis1, K Fiekert, M Johnston

  • 1Medair, Ecublens, Switzerland.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|October 1, 2004
PubMed

Insights

Tuberculosis infection risk in Kabul has significantly decreased since 1963. The average annual risk of infection (ARTI) is now 0.34%, a substantial drop from previous estimates, indicating improved public health outcomes.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Tuberculosis remains a global health concern, necessitating ongoing surveillance.
  • Understanding tuberculosis infection trends is crucial for effective control strategies.

Purpose of the Study:

  • To determine the prevalence and average annual risk of infection (ARTI) with Mycobacterium tuberculosis in Kabul, Afghanistan.
  • To assess changes in tuberculosis infection risk compared to previous surveys.

Main Methods:

  • A cluster sampling survey was conducted in Kabul from October to November 2000.
  • Tuberculin skin tests were administered to registered children, with infection prevalence determined using a cut-off point and mixture analysis.
  • Average ARTI was calculated algebraically from prevalence estimates.

Main Results:

  • The prevalence of tuberculous infection was estimated at 4.3% using a cut-off of >= 8 mm.
  • The average ARTI was calculated to be 0.61% using the cut-off method.
  • Mixture analysis estimated the average ARTI at 0.34% (95% CI: 0.23-0.54), a significant decrease from the 1963 estimate of 2.55%.

Conclusions:

  • There has been a substantial reduction in the risk of tuberculous infection in Kabul since 1963.
  • Despite past adverse conditions, the epidemiological situation regarding tuberculosis appears to have improved significantly.
Abstract

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