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[Primary renal angiosarcoma].

Cesáreo B Costero-Barrios¹, Cuauhtémoc Oros-Ovalle

¹Facultad de Medicina, Universidad Autónoma de San Luis Potosi, San Luis Potosí, México.

Gaceta Medica De Mexico

|October 1, 2004

Summary

This case study details a rare primary renal angiosarcoma in a 71-year-old male. Despite initial surgery, the patient experienced relapse, highlighting the aggressive nature of this kidney cancer.

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Area of Science:

Oncology
Pathology
Urology

Background:

Primary renal angiosarcoma is an exceptionally rare malignancy.
Understanding its presentation and behavior is crucial for diagnosis and treatment.

Observation:

A 71-year-old male presented with hematuria, flank pain, and a large left kidney mass (20 cm).
Computerized axial tomography (CT) confirmed the renal mass; a left nephrectomy was performed.
Histopathology revealed an angiosarcoma with atypical endothelial cell proliferation, positive for CD31 and CD34.

Findings:

The tumor replaced 4/5 of the kidney, weighing 1145g, with invasion of the parenchyma and capsule.
No metastases were detected initially, but the patient developed retroperitoneal and hepatic relapse 12 months post-surgery despite chemotherapy and radiotherapy.
Immunohistochemistry confirmed the diagnosis, differentiating it from benign vascular tumors and other sarcomas/carcinomas.

Implications:

This case underscores the aggressive potential and diagnostic challenges of primary renal angiosarcoma.
It highlights the importance of immunohistochemistry in differentiating vascular tumors of the kidney.
The study emphasizes the kidney's capacity to host diverse and rare neoplasms.

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