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Scedosporium apiospermum keratitis.

María José Linares Sicilia1, Manuel Santos Lacomba, Francisco Solís Cuesta

  • 1Departamento de Microbiología, Facultad de Medicina de Córdoba, Córdoba, Spain. mi1lisim@uco.es

Revista Iberoamericana De Micologia
|October 1, 2004
PubMed
Summary

A case of Scedosporium apiospermum keratitis, a fungal eye infection, occurred in a 65-year-old farmer. The patient recovered after treatment with amphotericin B.

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Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Background:

  • Fungal keratitis poses a significant threat to vision, especially in agricultural settings.
  • Scedosporium apiospermum is an emerging opportunistic fungal pathogen.
  • Corneal ulcers require prompt diagnosis and targeted treatment to prevent vision loss.

Observation:

  • A 65-year-old farmer presented with an extensive corneal ulcer in the left eye.
  • Direct examination of corneal scrapings revealed filamentous septate hyphae.
  • Fungal cultures were positive for Scedosporium apiospermum.

Findings:

  • Scedosporium apiospermum was identified as the causative agent of fungal keratitis.
  • The patient showed a successful clinical response to amphotericin B therapy.

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  • Early diagnosis and appropriate antifungal treatment are crucial for managing Scedosporium keratitis.

    • Implications:

    • This case highlights the importance of considering Scedosporium apiospermum in the differential diagnosis of fungal keratitis, particularly in farmers.
    • Amphotericin B remains an effective treatment option for Scedosporium apiospermum infections.
    • Further research into the epidemiology and optimal management of Scedosporium keratitis is warranted.