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Leptospirosis in the Seychelles.

T G Pinn1

  • 1Medical Department, Bundaberg Base Hospital.

The Medical Journal of Australia
|February 3, 1992
PubMed
Summary

Leptospirosis in the Seychelles is rat-borne, with an incidence of 60 per 100,000. Muscle pain and elevated creatine phosphokinase (CPK) are key early diagnostic indicators for this serious disease.

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Leptospirosis poses a significant public health concern globally.
  • Understanding the local epidemiology and transmission dynamics is crucial for effective control.

Purpose of the Study:

  • To determine the incidence of leptospirosis in Seychelles.
  • To identify sources and risk factors associated with leptospirosis.
  • To review diagnostic features and assess complications of the disease.

Main Methods:

  • A prospective survey was conducted over two years (1988-1990).
  • Cases diagnosed with leptospirosis at Victoria Hospital were included.
  • Serological confirmation and autopsy findings were utilized.

Main Results:

  • Eighty cases of leptospirosis were diagnosed, with 73% serologically confirmed.
  • Leptospira interrogans serovar icterohaemorrhagiae was the predominant identified serovar.
  • Myalgia (85%) and elevated creatine phosphokinase (CPK) levels (76%) were significant diagnostic aids, with earlier CPK elevation being more reliable.

Conclusions:

  • Leptospirosis in Seychelles is likely rat-borne, with an estimated annual incidence of 60 per 100,000.
  • The disease presented with significant mortality (16%).
  • Muscle tenderness and elevated CPK levels are valuable early diagnostic indicators.

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