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The ferret: an animal model to study influenza virus

John A Maher1, Joanne DeStefano

  • 1BioResources, Wyeth Research, Pearl River, NY, USA. MaherJ2@wyeth.com

Lab Animal
|October 1, 2004
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Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...