Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DNA microarrays: experimental issues, data analysis, and application to bacterial systems.

Yandi Dharmadi1, Ramon Gonzalez

  • 1Department of Chemical Engineering and Food Science & Human Nutrition, Iowa State University, 1035 Sweeney Hall, Ames, Iowa 50011, USA.

Biotechnology Progress
|October 2, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Planococcus dechangensis</i> NEAU-ST10-9<sup>T</sup> Promotes Maize Seedling Root Development: Evidence from Effective Fluorescence Tracking.

Microorganisms·2026
Same author

Engineering Yarrowia lipolytica as a next-generation biomanufacturing platform for sustainable lignocellulosic biorefineries.

Biotechnology advances·2026
Same author

Selective DNA encapsulation in extracellular vesicles of <i>Saccharomyces cerevisiae</i>.

Extracellular vesicles and circulating nucleic acids·2026
Same author

Harnessing Metalloprotease Wss1 to Enhance Methanol Utilization.

ACS synthetic biology·2026
Same author

Developing Topics.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Evaluation of compartmentalization systems to study microbial interactions.

Scientific reports·2025

DNA microarrays analyze bacterial gene expression changes. This review covers technology, experimental design, and data analysis for bacterial systems, highlighting future integration with other

Area of Science:

  • Microbiology
  • Genomics
  • Bioinformatics

Background:

  • DNA microarrays are established tools for studying organismal transcriptional responses to genetic and environmental factors.
  • While the technology has advanced, significant challenges remain in processing and analyzing transcriptome data beyond simple expression level quantification.

Purpose of the Study:

  • To review the technological aspects, experimental design considerations, and data analysis tools for DNA microarrays.
  • To present a comprehensive overview of DNA microarray applications in bacterial systems.

Main Methods:

  • Discussion of technological advancements and limitations of DNA microarrays.
  • Exploration of statistical and biological considerations for designing microarray experiments.
  • Review of statistical methodologies for analyzing microarray data.

Related Experiment Videos

Main Results:

  • Applications in bacterial systems are categorized into environmental response, gene identification/regulation, and genetic/metabolic engineering.
  • The potential of DNA microarrays is demonstrated, with a focus on bacterial research.

Conclusions:

  • Future integration of DNA microarrays with other 'omics' technologies (proteomics, metabolomics, etc.) will enhance understanding of genotype-phenotype relationships in bacteria.
  • This integrated approach will provide insights applicable to more complex organisms.