Related Experiment Video

Updated: Aug 21, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

The burden of kidney disease: improving global outcomes

Garabed Eknoyan1, Norbert Lameire, Rashad Barsoum

  • 1Baylor College of Medicine, Houston, Texas 77030, USA. geknoyan@bcm.tmc.edu

Kidney International
|October 2, 2004
PubMed

Insights

Chronic kidney disease (CKD) is a global health issue. Early detection and effective treatments can slow progression and reduce complications, highlighting the need for global CKD management strategies.

Area of Science:

  • Nephrology
  • Public Health
  • Global Health Initiatives

Background:

  • Chronic kidney disease (CKD) represents a significant global public health challenge.
  • Increasing incidence and prevalence of kidney failure necessitate urgent attention.
  • Earlier stages of CKD are common and linked to adverse outcomes like cardiovascular disease and mortality.

Purpose of the Study:

  • To address the worldwide epidemic of chronic kidney disease.
  • To establish a uniform and global public health approach for CKD management.
  • To introduce the "Kidney Disease: Improving Global Outcomes" (KDIGO) initiative.

Main Methods:

  • The initiative focuses on promoting coordination, collaboration, and integration of efforts.
  • Development and implementation of evidence-based clinical practice guidelines are central.
  • Leveraging universal scientific understanding of CKD care.

Main Results:

  • Early detection of CKD through laboratory testing is feasible.
  • Effective treatments exist to slow CKD progression.
  • Interventions can reduce cardiovascular events in CKD patients.

Conclusions:

  • A unified global strategy is essential for managing the CKD epidemic.
  • The KDIGO initiative aims to improve care and outcomes for kidney disease patients worldwide.
  • Standardized clinical practice guidelines are key to advancing global CKD care.

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...