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Updated: Aug 21, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Combined nonablative skin rejuvenation with the 595- and 1450-nm lasers
M A Trelles1, I Allones, J L Levy
1Instituto Médico Vilafortuny, Antoni de Gimbernat Foundation, Cambrils, Spain. imv@laser-spain.com
Background:
Histologic findings are not echoed in the visible effect in the epidermis after skin rejuvenation.
Subjects And Methods:
Ten women (Group A) received five treatment sessions with a 595-nm pulsed dye laser immediately followed by a 1450-nm diode laser. Two other demographically similar groups of 10 patients each, Groups B and C, were treated with the 595-nm pulsed dye laser or the 1450-nm diode laser alone, respectively.
Results:
Good dermal collagen remodeling was observed in Group A. Overall better and faster results were seen in Group A. The 6-month clinical outcome was best in Group A followed by Group C and Group B.
Conclusions:
Wavelengths of 595 plus 1450 nm for skin rejuvenation produced good results with much higher patient satisfaction than those obtained with the 595- or 1450-nm wavelengths alone.
