Angiolymphoid hyperplasia with eosinophilia associated to a squamous cell carcinoma of the ear
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Updated: Aug 21, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Alexander Lugo-Janer1, Lillian Montalvo, Hiram Ruiz-Santiago
1Department of Dermatology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Background:
Angiolymphoid hyperplasia with eosinophilia is a benign vascular proliferation that usually affects the head and neck region.
Method:
An 89-year-old man who had a squamous cell carcinoma on the posterior aspect of one ear developed lesions of angiolymphoid hyperplasia with eosinophilia on the anterior aspect of the same ear.
Results:
After surgical treatment of the malignant neoplasm, the lesions of angiolymphoid hyperplasia with eosinophilia disappeared spontaneously.
Conclusions:
Damage to the vasculature of the ear by the malignant neoplasm or the release of angiogenic factors by the same neoplasm is a plausible explanation for the development and eventual resolution of the vascular proliferation.