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Updated: Aug 21, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
A giant rheumatoid nodule
Takatomo Mine1, Hiroshi Tanaka, Tosihiko Taguchi
1Department of Orthopaedic Surgery, Yamaguchi University School of Medicine, Japan. tmine@po.cc.yamaguchi-u.ac.jp
Abstract:
Subcutaneous rheumatoid nodules occur commonly in advanced cases of rheumatoid arthritis and are the most common extra-articular lesion of this disease. We present a case of a very unusual giant rheumatoid nodule that developed on the lateral side of a knee. The case was devoid of systemic symptoms of arthritis and the lesion was limited to a rheumatoid nodule. The nodule was successfully treated by surgical excision. However, other new nodules developed in her hand. Her clinical course has not been satisfactory.
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