Related Experiment Video
Updated: Jul 17, 2026
04:55
A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
Published on: November 17, 2016
[Solid limbal dermoid in an 80-year-old patient]
P J Lang1, B Seitz, G O Naumann
1Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Erlangen.
Klinische Monatsblatter Fur Augenheilkunde
|October 2, 2004
Summary
This case report details an 80-year-old woman with a limbal dermoid, a benign tumor. While typically removed in childhood, this limbal dermoid was excised later in life due to its size and symptoms.
Area of Science:
- Ophthalmology
- Dermoid Tumors
- Ocular Oncology
Background:
- Solid limbal dermoids are usually surgically excised in pre-school aged children.
- Intervention may be earlier if high irregular astigmatism poses a risk for amblyopia.
Observation:
- An 80-year-old female presented with a two-month history of left eye irritation, foreign body sensation, and tearing.
- Ocular examination revealed a prominent, vascularized limbal tumor with secondary stromal lipoid deposits and deep anterior chamber penetration.
- Histological analysis confirmed a chronically irritated, predescemetal limbal dermoid with epidermalization and degenerative changes.
Findings:
- The limbal dermoid was excised in an elderly patient, deviating from the typical pre-school age intervention.
- Histopathology revealed significant secondary changes including epidermalization and elastoid degeneration.
Implications:
- Surgical excision of limbal dermoids is recommended in pre-school age when medically or cosmetically indicated.
- Lamellar excision is the preferred surgical approach for limbal dermoids.
