Related Experiment Video

Updated: Jul 28, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

The seroepidemiology of Hepatitis A virus in Amman, Jordan

M N G Battikhi1, E G Battikhi

  • 1Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, Hashemite University, Jordan.

The New Microbiologica
|October 6, 2004
PubMed

Insights

Hepatitis A virus (HAV) infections show seasonal patterns, peaking in spring and summer. Children aged 5-14 years were most affected by HAV in Jordan between 1991-2001.

Area of Science:

  • Hepatology
  • Virology
  • Public Health Epidemiology

Background:

  • Hepatitis A virus (HAV) poses a significant public health challenge in the Middle East, including Jordan.
  • Understanding HAV epidemiology is crucial for targeted public health interventions.

Purpose of the Study:

  • To analyze the epidemiological trends of Hepatitis A virus infections in Jordan.
  • To identify variations in HAV cases based on year, season, age, sex, and geographic district.

Main Methods:

  • Retrospective analysis of 1015 diagnosed Hepatitis A cases from January 1991 to December 2001.
  • Data collected from seventeen private laboratories across the Governorate of Amman, Jordan.
  • Statistical analysis to determine significant variations in HAV incidence.

Main Results:

  • Significant yearly variations in HAV cases were observed (P=0.03), with the highest incidence in 1993 and lowest in 2001.
  • HAV cases exhibited seasonal variation, with peaks in spring and summer months (P<0.001).
  • Age group 5-14 years had the highest number of cases (16.4%), and no significant sex variation was found (P=0.28).

Conclusions:

  • HAV infection occurrence is linked to age groups, year, and month in Jordan.
  • Epidemiological surveillance is essential for understanding and controlling Hepatitis A outbreaks.
  • Public health strategies should consider seasonal and age-specific risk factors for HAV prevention.

More Related Videos

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah04:43

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah

Published on: June 24, 2025

Hepatitis E Virus Fluorescence Reduction Neutralization Test for Measuring Neutralizing Antibody Titers07:58

Hepatitis E Virus Fluorescence Reduction Neutralization Test for Measuring Neutralizing Antibody Titers

Published on: May 22, 2026

Related Concept Videos

Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...