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Updated: Aug 21, 2026
Isolation of Peritoneum-derived Mast Cells and Their Functional Characterization with Ca2+-imaging and Degranulation Assays
Published on: July 4, 2018
The effects of castration and testosterone administration on mast cells and hydroxyproline in rat skin
M Hagiyama1, J Arata, K Tanioku
1Department of Dermatology, Okayama University Medical School, Okayama 700, Japan.
Abstract:
In rat skin of both sexes, significantly higher concentrations of mast cells were observed in the genital area as compared with the skin of the back. The hydroxyproline (HPL) value in the preputial skin was half that in the dorsal skin. The influence of castration and the administration of testosterone on male rat skin mast cells and HPL were investigated. A possible relationship was pointed out between HPL value and the mast cell population of the skin.
