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Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
A case of Schönlein-Henoch-purpura: an immunopathological study
1Department of Dermatology, Kawasaki Medical School, Kurashiki 701-01, Japan.
Abstract:
A case of Schonlein-Henoch-purpura is presented. The immunofluorescent study of skin lesions of the patient showed granular deposits of IgA and C3 in the blood vessel walls perivascular deposits of plasminogen and diffuse localization of fibrin and fibrinogen in the upper dermis. Complement activation via the alternative pathway through IgA, C3 and plasminogen deposits was suggested.
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