Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cerebral control of bladder function.

Derek J Griffiths1

  • 1Division of Geriatric Medicine, University of Pittsburgh, Room 547 NE, Montefiore Hospital, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA. GriffithsDJ@msx.dept-med.pitt.edu

Current Urology Reports
|October 6, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in brain response to urgency before and after treatment of urgency urinary incontinence with onabotulinumtoxin A.

Neurourology and urodynamics·2022
Same author

Testing a new, intensified infusion-withdrawal protocol for urinary urgency provocation in brain-bladder studies.

Neurourology and urodynamics·2020
Same author

Investigation of urinary storage symptoms in Parkinson's disease utilizing structural MRI techniques.

Neurourology and urodynamics·2019
Same author

Functional connectivity of the brain in older women with urgency urinary incontinence.

Neurourology and urodynamics·2018
Same author

Test-retest repeatability of patterns of brain activation provoked by bladder filling.

Neurourology and urodynamics·2016
Same author

The CNS and bladder dysfunction.

F1000 medicine reports·2012
Same journal

Effective Mentorship in Urology Fellowship Training: Qualities, Models, and Equity.

Current urology reports·2026
Same journal

Management of Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis.

Current urology reports·2026
Same journal

Lower Urinary Tract Symptoms as an Indicator of Occult Neurologic Disease: A System-first Framework for Urologic Practice.

Current urology reports·2026
Same journal

Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.

Current urology reports·2026
Same journal

Is Open Partial Nephrectomy Still an Option in the Robotic Era?

Current urology reports·2026
Same journal

Artificial Intelligence in Urologic Documentation: A Review of Emerging Capabilities and the Ongoing Need for Human Oversight.

Current urology reports·2026
See all related articles

Overactive bladder involves abnormal brain control networks. Brain imaging reveals altered responses to bladder filling in patients with poor bladder control, suggesting new treatment avenues.

Area of Science:

  • Neuroscience
  • Urology
  • Psychiatry

Background:

  • Overactive bladder is a common disorder affecting bladder control.
  • Normal bladder control relies on a complex emotional nervous system network.
  • This network processes bladder signals and motivates voiding for homeostasis.

Purpose of the Study:

  • To investigate the neural basis of bladder control.
  • To identify differences in brain activity during bladder filling in patients with overactive bladder.

Main Methods:

  • Functional brain imaging techniques, including positron emission tomography (PET) and functional magnetic resonance imaging (fMRI).
  • Analysis of brain responses in regions like the periaqueductal gray, thalamus, insula, anterior cingulate, and prefrontal cortex.

Related Experiment Videos

Main Results:

  • Normal bladder control involves a network including the periaqueductal gray, thalamus, insula, anterior cingulate, and prefrontal cortex.
  • Patients with poor bladder control exhibit abnormal brain responses to bladder filling.
  • Cerebral control abnormalities can exist even without involuntary detrusor contractions.

Conclusions:

  • Dysfunctional brain networks contribute to overactive bladder symptoms.
  • Altered brain activity patterns are identifiable in patients with bladder control disorders.
  • Behavioral therapy and electrical stimulation show promise as potential treatments for overactive bladder.