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Updated: Aug 21, 2026

Synchronous Triplanar Reconstruction Integrated with Color Doppler Mapping for Precise and Rapid Localization of Thyroid Lesions
Published on: February 9, 2024
[Current approaches to estimating the sizes of the thyroid in neonates and infants from ultrasonographic data]
Insights
Ultrasonography of the thyroid in preterm infants identified a new standard for thyroid volume. This allows for early detection of neonatal goiter and thyroid hypoplasia.
Area of Science:
- Neonatal medicine
- Endocrinology
- Medical imaging
Background:
- Thyroid function is crucial for infant development.
- Preterm infants are at higher risk for thyroid dysfunction.
- Early detection of thyroid abnormalities is essential.
Purpose of the Study:
- To ultrasonographically assess thyroid gland dimensions and echogenicity in preterm neonates.
- To develop a standard formula for thyroid volume in newborns.
- To enable early diagnosis of neonatal goiter and thyroid hypoplasia.
Main Methods:
- Ultrasound examination of the thyroid in 384 preterm infants (4-8 days old).
- Comparison of thyroid echogenicity with the parotid salivary gland.
- Development of a statistical formula for individual standard thyroid volume.
Main Results:
- Established a formula for calculating the standard thyroid volume in neonates.
- Demonstrated the feasibility of using ultrasonography for early thyroid assessment.
- Identified variations in thyroid size and echogenicity in infants born to mothers with iodine deficiency.
Conclusions:
- The developed formula provides a reliable method for assessing neonatal thyroid volume.
- Early ultrasonographic evaluation can aid in diagnosing thyroid abnormalities in preterm infants.
- This technique is valuable for managing potential endocrine issues in newborns.
Abstract:
The thyroid was ultrasonographically studied in 384 pre-term babies aged 4-8 days of life. The sizes of thyroid lobes were determined; the echogenicity of the thyroid was compared with that of the parotid salivary gland. The infants were born by apparently healthy mothers and females with iodine deficiency. An original procedure for neonatal ultrasound study was developed. Data statistical processing yielded a formula of the individual standard of a thyroid volume, which allows neonatal goiter and thyroid hypoplasia to be established at early stages of life.

