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Updated: Aug 21, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Carotenaemia in children is common and benign: most can stay at home
R McGowan1, J Beattie, P Galloway
1Acute Ambulatory Assessment Unit, Yorkhill NHS Trust, Glasgow.
Insights
Diet-related carotenaemia is common in children, often mistaken for serious illness. This review highlights the need for better recognition in primary care to avoid unnecessary hospital investigations for this benign condition.
Area of Science:
- Pediatric Nutrition
- Dermatology
- Clinical Diagnostics
Background:
- Carotenaemia, characterized by elevated plasma carotene levels, can present in children.
- Distinguishing benign, diet-related carotenaemia from other conditions is crucial for appropriate management.
Purpose of the Study:
- To review cases of elevated plasma carotene levels in children at a specific hospital.
- To assess the recognition and investigation of carotenaemia in primary and secondary care settings.
Main Methods:
- Retrospective case record review of children with elevated plasma carotene levels.
- Data collection on patient demographics, clinical presentation, and diagnostic workup.
Main Results:
- Thirty-one children were identified; 87% had simple diet-related carotenaemia and were otherwise well.
- Four cases of hypercarotenaemia indicated underlying nutritional issues and failure to thrive.
- The condition was recognized by a family doctor in only one case prior to referral.
- Many children underwent laboratory confirmation and repeat testing despite a clear dietary cause.
Conclusions:
- Diet-related carotenaemia is a common condition in the pediatric population.
- There is a significant lack of recognition within primary care, leading to potentially over-enthusiastic hospital investigations.
- Improved awareness can prevent unnecessary diagnostic procedures for benign carotenaemia.
Abstract:
We identified children with elevated plasma carotene levels who attended the Royal Hospital for Sick Children, Glasgow, between July 1998 and April 2001 and carried out a retrospective case record review. Thirty-one children were identified (7 boys; 14 girls) with a median age at presentation of 13 months (range 7m- 11yrs). Twenty-seven (87%) children had simple diet-related carotenaemia and were well. In four cases the hypercarotenaemia reflected nutritional problems with associated failure to thrive. In only one case did the family doctor recognise the condition before referral. Many who attended hospital had laboratory confirmation of the benign diagnosis despite a clear dietary origin. Some had repeat laboratory tests to confirm resolution. Diet-related carotenaemia appears common in our community. The condition appears poorly recognised within primary care and hospital investigations may be over-enthusiastic.
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