Biology of babesia

Recent advances in the knowledge of the biology of the protozoan family Babesiidae is reviewed with special emphasis on those species which cause economically important diseases in cattle. The life cycle of Babesia of cattle is illustrated taking into account these recent advances. Areas of controversy in the life cycles still exist particularly over the presence or absence of a sexual cycle within the tick vector and of exoerythrocytic schizonts in the mammalian host. In the mammalian host, the major parasite division cycle occurs in erythrocytes and it is these stages which induce the pathogenic effects. The recent progress in the understanding of the biology of Babesia parasites may allow important developments in the control of babesiosis.