Related Experiment Video
Updated: Aug 21, 2026

Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay
Published on: August 6, 2020
Antigen presentation and the response to parasitic infection
1Department of Tropical Hygiene, London School of Hygiene and Tropical Medicine, Keppel Street, London WCIE 7HT, UK.
Abstract:
Antigen presentation to T-cells is central to the induction and maintenance of the cell-mediated immune response. Many approaches have been used to define a complex accessory cell compartment, which performs the variety of functional roles encompassed by this term. Resulting from this, antigen presentation has become the cornerstone behind many theories of disease susceptibility and is an important consideration for vaccine design. In this article, Paul Kaye reviews aspects of antigen presentation by accessory cells with particular emphasis on how parasites and their antigens interact with this heterogeneous group of cells.
Related Concept Videos
Malaria
Antigen Presenting Cells
T cells require the help of antigen-presenting cells (APCs), which process foreign antigens into smaller fragments that can be recognized by T cells. These APCs are highly specialized cells that efficiently internalize antigens...
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Antigen Processing Pathways
MHC Class I: Presenting Endogenous...
Cell-mediated Immune Responses
Toxoplasmosis
